5-MeO-DMT is a very interesting substance indeed. 5-MeO-DMT is closely related to N,N-dimethyltryptamine but produces quite different effects. It is considered to be up to six times more powerful than N,N-dimethyltryptamine, which may be hard to imagine for anyone who has only experienced the latter. 5-MeO-DMT stands for 5-Methoxy-N,N-dimethyltryptamine. The molecular structure looks like that of N,N-dimethyltryptamine but has extra atoms attached, which leads to a different experience when consuming it. DMT Extraction
5-MeO-DMT can be sourced from various shrubs and trees, but it is more famously extracted from the skin glands of the Bufo alvarius or Incilius alvarius toad (also known as the Colorado River toad or Sonoron Desert toad). Like DMT, today 5-MeO-DMT is widely used as an entheogen (i.e. as a means of experiencing unity with the creator through the altered state it provides).
Evidence suggests a long history of 5-MeO-DMT in the Americas, perhaps dating back even thousands of years. It has been used ceremonially and ritualistically, but not all indigenous cultures embrace the substance as a medicine.
Since research into 5-MeO-DMT EXtraction is still in its early stages and by no means conclusive, it is hard to verify the truth of specific therapeutic qualities such as addiction recovery. Furthermore, although there are treatment centres using it in combination with other psychoactive substances such as ayahuasca or iboga, some feel that this is a dangerous endeavour. Indolealkylamines (which includes 5-MeO-DMT) may cause serotonin syndrome if too much is taken or they are used in combination with other substances. Negative interactions with monoamine oxidase inhibitors (MAOIs) have been reported – in particular harmine or harmaline.
With regards to plant extractions, it is necessary to extract with care, since there have been cases of toxicity in some plant strains. This report refers to an effect on animals, and gramine toxicity has been known to cause cardiac arrest in sheep. Nevertheless, when preparing any psychoactive substance, it pays to do your research properly and understand the physical and psychological risks.
Vegans are unlikely to approve of the toad venom extraction techniques, since it involves exciting (or what some might call traumatising) the toads in order to get them to secrete their poison. There is much debate about owning toads and taking them out of their natural habitat for personal or commercial gain.
Have you had a 5-MeO-DMT experience that you’d like to share on DMT Times? We are currently looking for experiences for our library of DMT experiences, so get in touch or submit your experience via the online form if you wish to share yours.
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